Active life: 14-16 days
Drug class: Anabolic/Androgenic steroid (for injection)
Average dose: Men 300 - 800 mg/week; Woman 50-100 mg/week
Water retention: Yes, but less than Testosterone
High blood pressure: Dose dependent
Liver toxic: No
Aromatization: Low, converts to less active norestrogens
DHT Conversion: No, converts to NOR DHT which is less active than DHT
Decreased HPTA function: Yes, severe
Nandrolone Decanoate is classified as a 19-nor compound as it lacks the 19th carbon that Testosterone has which classifies it as a Progestin and therefore express an affinity for the Progesterone receptor. Nandrolone Decanoate is slightly stronger than Testosterone where anabolism is concerned, with a strength rating of 125 and by comparison Testosterone’s anabolic strength rating is 100. Nandrolone also possesses a very low androgenic rating of 37, making it favorable for those who are either sensitive to or with to avoid androgenic side effects (Testosterone is 100).
Nandrolone possesses very low Estrogenic activity and binds dismally with the aromatase enzyme, which is the enzyme responsible for the conversion of androgens into Estrogen. Approximately 20% of Nandrolone is converted into Estrogen in comparison to Testosterone’s conversion rate. Due to Nandrolone being classified as a Progestin, is what contributes to its low estrogenic activity. Nandrolone’s aromatization into Estrogen occurs in the liver.
The claim that Nandrolone Decanoate is good for the joints and bone tissue is indeed true. Nandrolone promotes significant increases in collagen synthesis, more so than any other anabolic steroids. The myth of Nandrolone lubricating the joints is a farce. Nandrolone has also demonstrated an ability to promote increases in bone mineral content. This allows athletes to experience positive effects on connective and joint tissue, strengthening them during strength and muscle gaining cycles.
Nandrolone has a very low aromatization rate into Estrogen which makes its estrogenic side effects less of an issue compared to other anabolic steroids. Although Estrogen related side effects are not totally and utterly eliminated with Nandrolone, it is far less prominent than most anabolic steroids. Estrogenic side effects can include water retention, blood pressure increases as a result of water retention, and gynecomastia.
Progesterone and Prolactin related issues can manifest in the form of side effects that are very similar to Estrogen – puffy nipples, gynecomastia, bloating, etc. Anti-estrogens and aromatase inhibitors are known for combating these side effects effectively and efficiently. The use of vitamin B6 has been known to control Prolactin levels at dosages of 600mg daily. Cabergoline and Bromocriptine (Anti-prolactin drugs) are effective at reducing elevated Prolactin levels in the body to counteract the abovementioned side-effects.
Nandrolone does cause disruption and shutdown of the HPTA (Hypothalamic Pituitary Testicular Axis), This is common of any 19-nor steroid, and rapid suppression is due to it being a Progestin by nature.
Nandrolone Decanoate has shown to decrease HDL “good” cholesterol” levels by 26% over 10 weeks of use. If compared with Testosterone, it tends to have far worse cholesterol side-effects than Testosterone. It is also known to be up to 11 times more damaging to blood vessels than Testosterone.
Therapeutic dosages range between 50 – 100mg every 3 – 4 weeks, for no longer than 12 weeks. Beginner athletes may utilize it in the range of 300 – 500mg per week. Intermediate users normally use around the 500mg mark especially when Nandrolone is stacked with other compounds such as Testosterone and/or another oral compounds such as Anapolon (Oxymetholone), Dianabol (Methandrostenolone) or Oral Turinabol (Chlordehydromethyltestosterone). Advanced users should find a range of approximately 600 – 800mg or greater should suffice, especially if Nandrolone is the primary anabolic compound and Testosterone is run at a TRT (Testosterone Replacement Therapy) dose.
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